Publications

2025

Karsten Rippe, Argyris Papantonis (2025) RNA polymerase II transcription compartments — from factories to condensates, Nature Reviews Genetics 2025, p. 1-14, Nature Publishing Group, url, doi:10.1038/s41576-025-00859-6

Argyris Papantonis, A. Marieke Oudelaar (2025) Mechanisms of Enhancer-Mediated Gene Activation in the Context of the 3D Genome, Annual review of genomics and human genetics, Annu Rev Genomics Hum Genet, url, doi:10.1146/ANNUREV-GENOM-120423-012301

Argyris Papantonis, A. Marieke Oudelaar (2025) Mechanisms of Enhancer-Mediated Gene Activation in the Context of the 3D Genome, Annual Review of Genomics and Human Genetics, Annual Reviews, url, doi:10.1146/ANNUREV-GENOM-120423-012301

Magdalena A. Karpinska, Yi Zhu, Zahra Fakhraei Ghazvini, Shyam Ramasamy, Mariano Barbieri, T. B.Ngoc Cao, Natalie Varahram, Abrar Aljahani, Michael Lidschreiber, Argyris Papantonis, A. Marieke Oudelaar (2025) CTCF depletion decouples enhancer-mediated gene activation from chromatin hub formation, Nature Structural & Molecular Biology 2025, p. 1-14, Nature Publishing Group, url, doi:10.1038/s41594-025-01555-z

Indrani Bhattacharya, Alexander Hautke, Emma Rossi, Laurie Stevens, Aritra Marick, Asesh Bera, Tanushree Das, Alberta Ferrarini, Marialore Sulpizi, Simon Ebbinghaus, Rajib Kumar Mitra (2025) Non-monotonous Concentration Dependent Solvation of ATP Could Help to Rationalize Its Anomalous Impact on Various Biophysical Processes, Journal of Physical Chemistry Letters 16, p. 4305-4314, American Chemical Society, url, doi:10.1021/ACS.JPCLETT.5C00338/ASSET/IMAGES/LARGE/JZ5C00338_0006.JPEG

Benjamin Lenzen, Florian Rösch, Julia Legen, Hannes Ruwe, Nitin Kachariya, Michael Sattler, Ian Small, Christian Schmitz-Linneweber (2025) The chloroplast RNA–binding protein CP29A supports rbcL expression during cold acclimation, Proceedings of the National Academy of Sciences of the United States of America 122(5), p. e2403969122, National Academy of Sciences, url, doi:10.1073/PNAS.2403969122/SUPPL_FILE/PNAS.2403969122.SAPP.PDF

Carla Volkert, Mateusz Brzezinski, Pablo Gomez Argudo, Renan Colucci, Sapun H. Parekh, Pol Besenius, Jasper J. Michels, Ulrike Kraft (2025) Enhanced Electrical Performance and Stretchability by Plasticizer-Facilitated PEDOT:PSS Self-Alignment, Advanced Science, p. 2502853, John Wiley and Sons Inc, url, doi:10.1002/ADVS.202502853;WGROUP:STRING:PUBLICATION

Ivar S. Haugerud, Hidde D. Vuijk, Job Boekhoven, Christoph A. Weber (2025) Excitability and oscillations of active droplets, url

Daxiao Sun, Xueping Zhao, Tina Wiegand, Anthony A Hyman, Christoph Weber, Alf Honigmann Correspondence, Cecilie Martin-Lemaitre, Tom Borianne, Lennart Kleinschmidt, Stephan W Grill, Alf Honigmann (2025) Assembly of tight junction belts by ZO1 surface condensation and local actin polymerization, Developmental Cell 60(8), p. 1234-1250.e6, Elsevier, url, doi:10.1016/J.DEVCEL.2024.12.012

Xueping Zhao, Daxiao Sun, Giacomo Bartolucci, Anthony A. Hyman, Alf Honigmann, Christoph A. Weber (2025) Theory of non-dilute binding and surface phase separation applied to membrane-binding proteins, bioRxiv, p. 2024.12.31.630850, Cold Spring Harbor Laboratory, url, doi:10.1101/2024.12.31.630850

2024

Spiros Palikyras, Vassiliki Varamogiani-Mamatsi, Yajie Zhu, Shyam Ramasamy, Athanasia Mizi, Isabel Liebermann, Athanasia Stavropoulou, Ioanna Papadionysiou, Deniz Bartsch, Yulia Kargapolova, Konstantinos Sofiadis, Christoforos Nikolaou, Leo Kurian, A. Marieke Oudelaar, Mariano Barbieri, Argyris Papantonis (2024) Senescent cells cluster CTCF on nuclear speckles to sustain their splicing program, bioRxiv, p. 2024.07.16.603680, Cold Spring Harbor Laboratory, url, doi:10.1101/2024.07.16.603680

Angeliki Platania, Cathie Erb, Mariano Barbieri, Bastien Molcrette, Erwan Grandgirard, Marit A.C. de Kort, Wim Pomp, Karen Meaburn, Tiegh Taylor, Virlana M. Shchuka, Silvia Kocanova, Mariia Nazarova, Guilherme Monteiro Oliveira, Jennifer A. Mitchell, Evi Soutoglou, Tineke L. Lenstra, Nacho Molina, Argyris Papantonis, Kerstin Bystricky, Tom Sexton (2024) Transcription processes compete with loop extrusion to homogenize promoter and enhancer dynamics, Science advances 10(50), p. eadq0987, American Association for the Advancement of Science, url, doi:10.1126/SCIADV.ADQ0987/SUPPL_FILE/SCIADV.ADQ0987_DATA_S1_TO_S3.ZIP

Robin Weinmann, Arjun Udupa, Jan Fabio Nickels, Lukas Frank, Caroline Knotz, Karsten Rippe (2024) HP1 binding creates a local barrier against transcription activation and persists during chromatin decondensation, bioRxiv, p. 2024.12.09.627308, Cold Spring Harbor Laboratory, url, doi:10.1101/2024.12.09.627308

Roland Pollak, Leon Koch, Benedikt König, Sara S. Ribeiro, Nirnay Samanta, Klaus Huber, Simon Ebbinghaus (2024) Cell stress and phase separation stabilize the monomeric state of pseudoisocyanine chloride employed as a self-assembly crowding sensor, Communications Chemistry 2024 7:1 7(1), p. 1-8, Nature Publishing Group, url, doi:10.1038/s42004-024-01315-y

Julia Legen, Benjamin Lenzen, Nitin Kachariya, Stephanie Feltgen, Yang Gao, Simon Mergenthal, Willi Weber, Enrico Klotzsch, Reimo Zoschke, Michael Sattler, Christian Schmitz-Linneweber (2024) A prion-like domain is required for phase separation and chloroplast RNA processing during cold acclimation in Arabidopsis, The Plant Cell 36(8), p. 2851-2872, Oxford Academic, url, doi:10.1093/PLCELL/KOAE145

Yanning Wang, Shulin Li, Marcel Mokbel, Alexander I. May, Zizhen Liang, Yonglun Zeng, Weiqi Wang, Honghong Zhang, Feifei Yu, Katharina Sporbeck, Liwen Jiang, Sebastian Aland, Jaime Agudo-Canalejo, Roland L. Knorr, Xiaofeng Fang (2024) Biomolecular condensates mediate bending and scission of endosome membranes, Nature 2024 634:8036 634(8036), p. 1204-1210, Nature Publishing Group, url, doi:10.1038/s41586-024-07990-0

Mateusz Brzezinski, Pablo G. Argudo, Tom Scheidt, Miao Yu, Elnaz Hosseini, Anke Kaltbeitzel, Edward A. Lemke, Jasper J. Michels, Sapun H. Parekh (2024) Protein-Specific Crowding Accelerates Aging in Protein Condensates, Biomacromolecules, American Chemical Society, url, doi:10.1021/ACS.BIOMAC.4C00609/ASSET/IMAGES/LARGE/BM4C00609_0005.JPEG

Terra M. Kuhn, Malte Paulsen, Sara Cuylen-Haering (2024) Accessible high-speed image-activated cell sorting, Trends in Cell Biology 34(8), p. 657-670, Elsevier Current Trends, url, doi:10.1016/J.TCB.2024.04.007

Alberto Hernandez-Armendariz, Valerio Sorichetti, Yuki Hayashi, Zuzana Koskova, Andreas Brunner, Jan Ellenberg, Anđela Šarić, Sara Cuylen-Haering (2024) A liquid-like coat mediates chromosome clustering during mitotic exit, Molecular Cell 84(17), p. 3254-3270.e9, Cell Press, url, doi:10.1016/J.MOLCEL.2024.07.022

Timon Beck, Lize-Mari van der Linden, Wade M. Borcherds, Kyoohyun Kim, Raimund Schlüßler, Paul Müller, Titus M. Franzmann, Conrad Möckel, Ruchi Goswami, Mark Leaver, Tanja Mittag, Simon Alberti, Jochen Guck (2024) Optical characterization of molecular interaction strength in protein condensates, Molecular Biology of the Cell 35(12), Jeffrey Woodruff (ed.), p. ar154, url, doi:10.1091/MBC.E24-03-0128

Giacomo Bartolucci, Ivar S Haugerud, Thomas CT Michaels, Christoph A Weber (2024) The interplay between biomolecular assembly and phase separation, eLife 13, eLife Sciences Publications Limited, url, doi:10.7554/ELIFE.93003.2

Mateusz Brzezinski, Pablo G. Argudo, Tom Scheidt, Miao Yu, Elnaz Hosseini, Anke Kaltbeitzel, Edward A. Lemke, Jasper J. Michels, Sapun H. Parekh (2024) Protein-Specific Crowding Accelerates Aging in Protein Condensates, Biomacromolecules, American Chemical Society, url, doi:10.1021/ACS.BIOMAC.4C00609

2023

Robin Weinmann, Lukas Frank, Karsten Rippe (2023) Approaches to characterize chromatin subcompartment organization in the cell nucleus, Current Opinion in Structural Biology 83, Elsevier Ltd, url, doi:10.1016/j.sbi.2023.102695

Anne Rademacher, Fabian Erdel, Robin Weinmann, Karsten Rippe (2023) Assessing the Phase Separation Propensity of Proteins in Living Cells Through Optodroplet Formation, Methods in Molecular Biology 2563, p. 395-411, Humana Press Inc., url, doi:10.1007/978-1-0716-2663-4_20,

Alexander Hautke, Arthur Voronin, Fathia Idiris, Anton Riel, Felix Lindner, Amandine Lelièvre-Büttner, Jikang Zhu, Bettina Appel, Edoardo Fatti, Karsten Weis, Sabine Müller, Alexander Schug, Simon Ebbinghaus (2023) CAG-Repeat RNA Hairpin Folding and Recruitment to Nuclear Speckles with a Pivotal Role of ATP as a Cosolute, Journal of the American Chemical Society 145(17), p. 9571-9583, American Chemical Society, url, doi:10.1021/JACS.2C13653/ASSET/IMAGES/LARGE/JA2C13653_0007.JPEG

Alexander Hautke, Simon Ebbinghaus (2023) The emerging role of ATP as a cosolute for biomolecular processes, Biological Chemistry 404(10), p. 897-908, Walter de Gruyter GmbH, url, doi:10.1515/HSZ-2023-0202/ASSET/GRAPHIC/J_HSZ-2023-0202_FIG_004.JPG

Susanne Liese, Xueping Zhao, Christoph A. Weber, Frank JĂĽlicher (2023) Chemically Active Wetting, Proceedings of the National Academy of Sciences 122(15), p. e2403083122, National Academy of Sciences, url, doi:10.1073/PNAS.2403083122/SUPPL_FILE/PNAS.2403083122.SAPP.PDF

Mariana Juliani  do Amaral, Satabdee Mohapatra, Aline Ribeiro Passos, Taiana Sousa  Lopes da Silva, Renato Sampaio Carvalho, Marcius  da Silva Almeida, Anderson Sá Pinheiro, Susanne Wegmann, Yraima Cordeiro (2023) Copper drives prion protein phase separation and modulates aggregation, Science Advances 9(44), American Association for the Advancement of Science, url, doi:10.1126/SCIADV.ADI7347

Herman K.H. Fung, Yuki Hayashi, Veijo T. Salo, Anastasiia Babenko, Ievgeniia Zagoriy, Andreas Brunner, Jan Ellenberg, Christoph W. MĂĽller, Sara Cuylen-Haering, Julia Mahamid (2023) Genetically encoded multimeric tags for subcellular protein localization in cryo-EM, Nature Methods 2023, p. 1-9, Nature Publishing Group, url, doi:10.1038/s41592-023-02053-0

Miao Yu, Maziar Heidari, Sofya Mikhaleva, Piau Siong Tan, Sara Mingu, Hao Ruan, Christopher D Reinkemeier, Agnieszka Obarska-Kosinska, Marc Siggel, Martin Beck, Gerhard Hummer, Edward A Lemke (2023) Visualizing the disordered nuclear transport machinery in situ, | Nature | 617, url, doi:10.1038/s41586-023-05990-0

Satabdee Mohapatra, Susanne Wegmann (2023) Biomolecular condensation involving the cytoskeleton, Brain research bulletin 194, Brain Res Bull, url, doi:10.1016/J.BRAINRESBULL.2023.01.009

Prabhu Rajaiah Prince, Janine Hochmair, Hévila Brognaro, Susanna Gevorgyan, Maximilian Franck, Robin Schubert, Kristina Lorenzen, Selin Yazici, Eckhard Mandelkow, Susanne Wegmann, Christian Betzel (2023) Initiation and modulation of Tau protein phase separation by the drug suramin, Scientific reports 13(1), p. 3963, Sci Rep, url, doi:10.1038/S41598-023-29846-9

Anja Konietzny, Susanne Wegmann, Marina Mikhaylova (2023) The endoplasmic reticulum puts a new spin on synaptic tagging, Trends in Neurosciences 46(1), p. 32-44, Elsevier Current Trends, doi:10.1016/J.TINS.2022.10.012

Janine Hochmair, Christian Exner, Christian Betzel, Eckhard Mandelkow, Susanne Wegmann (2023) Light Microscopy and Dynamic Light Scattering to Study Liquid-Liquid Phase Separation of Tau Proteins In Vitro, Methods in Molecular Biology 2551, p. 225-243, Humana Press Inc., url, doi:10.1007/978-1-0716-2597-2_15/FIGURES/4

2022

Graeme J. Thorn, Christopher T. Clarkson, Anne Rademacher, Hulkar Mamayusupova, Gunnar Schotta, Karsten Rippe, Vladimir B. Teif (2022) DNA sequence-dependent formation of heterochromatin nanodomains, Nature Communications 2022 13:1 13(1), p. 1-13, Nature Publishing Group, url, doi:10.1038/s41467-022-29360-y

Karsten Rippe, Argyris Papantonis (2022) Functional organization of RNA polymerase II in nuclear subcompartments, Current Opinion in Cell Biology 74, p. 88-96, Elsevier Ltd, url, doi:10.1016/j.ceb.2022.01.005

Karsten Rippe (2022) Liquid–Liquid Phase Separation in Chromatin, Cold Spring Harbor Perspectives in Biology 14(2), Cold Spring Harbor Laboratory Press, url, doi:10.1101/CSHPERSPECT.A040683,

Jorge Trojanowski, Lukas Frank, Anne Rademacher, Norbert MĂĽcke, Pranas Grigaitis, Karsten Rippe (2022) Transcription activation is enhanced by multivalent interactions independent of phase separation, Molecular Cell 82(10), p. 1878-1893.e10, Cell Press, url, doi:10.1016/J.MOLCEL.2022.04.017

Nirnay Samanta, Yasser B. Ruiz-Blanco, Zamira Fetahaj, David Gnutt, Carter Lantz, Joseph A. Loo, Elsa Sanchez-Garcia, Simon Ebbinghaus (2022) Superoxide Dismutase 1 Folding Stability as a Target for Molecular Tweezers in SOD1-Related Amyotrophic Lateral Sclerosis, ChemBioChem 23(21), p. e202200396, John Wiley and Sons Inc, url, doi:10.1002/CBIC.202200396;WEBSITE:WEBSITE:CHEMISTRY-EUROPE;REQUESTEDJOURNAL:JOURNAL:14397633;WGROUP:STRING:PUBLICATION

Daniel Schraivogel, Terra M. Kuhn, Benedikt Rauscher, Marta Rodríguez-Martínez, Malte Paulsen, Keegan Owsley, Aaron Middlebrook, Christian Tischer, Beáta Ramasz, Diana Ordoñez-Rueda, Martina Dees, Sara Cuylen-Haering, Eric Diebold, Lars M. Steinmetz (2022) High-speed fluorescence image-enabled cell sorting, Science 375(6578), p. 315-320, American Association for the Advancement of Science, url, doi:10.1126/SCIENCE.ABJ3013/SUPPL_FILE/SCIENCE.ABJ3013_MDAR_REPRODUCIBILITY_CHECKLIST.PDF

Daniel Schraivogel, Terra M. Kuhn, Benedikt Rauscher, Marta Rodríguez-Martínez, Malte Paulsen, Keegan Owsley, Aaron Middlebrook, Christian Tischer, Beáta Ramasz, Diana Ordoñez-Rueda, Martina Dees, Sara Cuylen-Haering, Eric Diebold, Lars M. Steinmetz (2022) High-speed fluorescence image-enabled cell sorting, Science 375(6578), p. 315-320, American Association for the Advancement of Science, url, doi:10.1126/SCIENCE.ABJ3013/SUPPL_FILE/SCIENCE.ABJ3013_MDAR_REPRODUCIBILITY_CHECKLIST.PDF

Raimund Schlüßler, Kyoohyun Kim, Martin Nötzel, Anna Taubenberger, Shada Abuhattum, Timon Beck, Paul Müller, Shovamayee Maharana, Gheorghe Cojoc, Salvatore Girardo, Andreas Hermann, Simon Alberti, Jochen Guck (2022) Correlative all-optical quantification of mass density and mechanics of subcellular compartments with fluorescence specificity, eLife 11, p. 68490, eLife Sciences Publications, Ltd, url, doi:10.7554/ELIFE.68490

Janine Hochmair, Christian Exner, Maximilian Franck, Alvaro Dominguez-Baquero, Lisa Diez, H Evila Brognaro, Matthew L Kraushar, Thorsten Mielke, Helena Radbruch, Senthil Kaniyappan, Sven Falke, Eckhard Mandelkow, Christian Betzel, Susanne Wegmann (2022) Molecular crowding and RNA synergize to promote phase separation, microtubule interaction, and seeding of Tau condensates, The EMBO Journal, p. e108882, John Wiley & Sons, Ltd, url, doi:10.15252/EMBJ.2021108882

LA Gruijs da Silva, D Dormann (2022) Sedimentation assays to assess the impact of post-translational modifications on phase separation of RNA-binding proteins in vitro and in cells, Methods Mol Biol, in press

LA Gruijs da Silva, F Simonetti, S Hutten, H Riemenschneider, EL Sternburg, LM Pietrek, J Gebel, V Doetsch, D Edbauer, G Hummer, LS Stelzl, D Dormann (2022) Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation, EMBO J, in press

Erin L. Sternburg, Lara A. Gruijs da Silva, Dorothee Dormann (2022) Post-translational modifications on RNA-binding proteins: accelerators, brakes, or passengers in neurodegeneration?, Trends in biochemical sciences 47(1), p. 6-22, Trends Biochem Sci, url, doi:10.1016/J.TIBS.2021.07.004

2021

Karsten Rippe, Argyris Papantonis (2021) RNA polymerase II transcription compartments: from multivalent chromatin binding to liquid droplet formation?, Nature Reviews Molecular Cell Biology 22(10), p. 645-646, Nature Research, url, doi:10.1038/S41580-021-00401-6;SUBJMETA=337,386,572,631,80;KWRD=NUCLEAR+ORGANIZATION,TRANSCRIPTION

Karsten Rippe, Argyris Papantonis (2021) RNA polymerase II transcription compartments: from multivalent chromatin binding to liquid droplet formation?, Nature Reviews Molecular Cell Biology 22(10), p. 645-646, Nature Research, url, doi:10.1038/S41580-021-00401-6;SUBJMETA=337,386,572,631,80;KWRD=NUCLEAR+ORGANIZATION,TRANSCRIPTION

Anatol W. Fritsch, Andres F. Diaz-Delgadillo, Omar Adame-Arana, Carsten Hoege, Matthaus Mittasch, Moritz Kreysing, Mark Leaver, Anthony A. Hyman, Frank Julicher, Christoph A. Weber (2021) Local thermodynamics govern formation and dissolution of Caenorhabditis elegans P granule condensates, Proceedings of the National Academy of Sciences of the United States of America 118(37), p. e2102772118, National Academy of Sciences, url, doi:10.1073/PNAS.2102772118/SUPPL_FILE/PNAS.2102772118.SM01.MP4

Anatol W. Fritsch, Andres F. Diaz-Delgadillo, Omar Adame-Arana, Carsten Hoege, Matthaus Mittasch, Moritz Kreysing, Mark Leaver, Anthony A. Hyman, Frank Julicher, Christoph A. Weber (2021) Local thermodynamics govern formation and dissolution of Caenorhabditis elegans P granule condensates, Proceedings of the National Academy of Sciences of the United States of America 118(37), p. e2102772118, National Academy of Sciences, url, doi:10.1073/PNAS.2102772118/SUPPL_FILE/PNAS.2102772118.SM01.MP4

Nirnay Samanta, Sara S. Ribeiro, Mailin Becker, Emeline Laborie, Roland Pollak, Stepan Timr, Fabio Sterpone, Simon Ebbinghaus (2021) Sequestration of Proteins in Stress Granules Relies on the In-Cell but Not the in Vitro Folding Stability, Journal of the American Chemical Society 143(47), p. 19909-19918, American Chemical Society, url, doi:10.1021/JACS.1C09589/SUPPL_FILE/JA1C09589_SI_001.PDF

Hamideh Hajiabadi, Irina Mamontova, Roshan Prizak, Agnieszka Pancholi, Anne Koziolek, Lennart Hilbert (2021) Deep-learning microscopy image reconstruction with quality control reveals second-scale rearrangements in RNA polymerase II clusters, bioRxiv, p. 2021.12.05.471272, Cold Spring Harbor Laboratory, url, doi:10.1101/2021.12.05.471272

Giacomo Bartolucci, Omar Adame-Arana, Xueping Zhao, Christoph A. Weber (2021) Controlling composition of coexisting phases via molecular transitions, Biophysical Journal 120(21), p. 4682-4697, Elsevier, url, doi:10.1016/j.bpj.2021.09.036

Xueping Zhao, Giacomo Bartolucci, Alf Honigmann, Frank JĂĽlicher, Christoph A Weber (2021) Thermodynamics of wetting, prewetting and surface phase transitions with surface binding, New Journal of Physics 23(12), p. 123003, IOP Publishing, url, doi:10.1088/1367-2630/ac320b

Lars Hubatsch, Louise M. Jawerth, Celina Love, Jonathan Bauermann, T. Y.Dora Tang, Stefano Bo, Anthony A. Hyman, Christoph A. Weber (2021) Quantitative theory for the diffusive dynamics of liquid condensates, eLife 10, eLife Sciences Publications Ltd, doi:10.7554/eLife.68620

Salma Sohrabi-Jahromi, Johannes Söding (2021) Thermodynamic modeling reveals widespread multivalent binding by RNA-binding proteins, Bioinformatics 37(Supplement_1), p. I308-I316, Oxford Academic, url, doi:10.1093/bioinformatics/btab300

Chad A. Sallaberry, Barbie J. Voss, Jaroslaw Majewski, Jacek Biernat, Eckhard Mandelkow, Eva Y. Chi, Crystal M. Vander Zanden (2021) Tau and Membranes: Interactions That Promote Folding and Condensation, Frontiers in Cell and Developmental Biology 9, Front Cell Dev Biol, url, doi:10.3389/fcell.2021.725241

Adriana Savastano, David Flores, Harindranath Kadavath, Jacek Biernat, Eckhard Mandelkow, Markus Zweckstetter (2021) Disease-Associated Tau Phosphorylation Hinders Tubulin Assembly within Tau Condensates, Angewandte Chemie - International Edition 60(2), p. 726-730, John Wiley & Sons, Ltd, url, doi:10.1002/anie.202011157

Susanne Wegmann, Jacek Biernat, Eckhard Mandelkow (2021) A current view on Tau protein phosphorylation in Alzheimer's disease, Current Opinion in Neurobiology 69, p. 131-138, Curr Opin Neurobiol, url, doi:10.1016/j.conb.2021.03.003

Prashant Rawat, Marc Boehning, Barbara Hummel, Fernando Aprile-Garcia, Anwit S. Pandit, Nathalie Eisenhardt, Ashkan Khavaran, Einari Niskanen, Seychelle M. Vos, Jorma J. Palvimo, Andrea Pichler, Patrick Cramer, Ritwick Sawarkar (2021) Stress-induced nuclear condensation of NELF drives transcriptional downregulation, Molecular Cell 81(5), p. 1013-1026.e11, Mol Cell, url, doi:10.1016/j.molcel.2021.01.016

Jasper J. Michels, Mateusz Brzezinski, Tom Scheidt, Edward A. Lemke, Sapun H. Parekh (2021) Role of Solvent Compatibility in the Phase Behavior of Binary Solutions of Weakly Associating Multivalent Polymers, Biomacromolecules 15, p. acs.biomac.1c01301, American Chemical Society, url, doi:10.1021/ACS.BIOMAC.1C01301

Sayantan Chatterjee, Yelena Kan, Mateusz Brzezinski, Kaloian Koynov, Roshan Mammen Regy, Anastasia C. Murthy, Kathleen A. Burke, Jasper J. Michels, Jeetain Mittal, Nicolas L. Fawzi, Sapun H. Parekh (2021) Reversible Kinetic Trapping of FUS Biomolecular Condensates, Advanced Science, p. 2104247, John Wiley & Sons, Ltd, url, doi:10.1002/ADVS.202104247

Lukas Frank, Robin Weinmann, Fabian Erdel, Jorge Trojanowski, Karsten Rippe (2021) Transcriptional Activation of Heterochromatin by Recruitment of dCas9 Activators, Enhancer and Promotors. Methods in Molecular Biology 2351, T. Borggrefe, B.D. Giaimo (ed.), p. 307-320, Humana, New York, NY, url, doi:10.1007/978-1-0716-1597-3_17

Jorge Trojanowski, Lukas Frank, Anne Rademacher, Pranas Grigaitis, Karsten Rippe (2021) Transcription activation is enhanced by multivalent interactions independent of liquid-liquid phase separation, bioRxiv, p. 2021.01.27.428421, Cold Spring Harbor Laboratory, url, doi:10.1101/2021.01.27.428421

Amra Noa, Hui Shun Kuan, Vera Aschmann, Vasily Zaburdaev, Lennart Hilbert (2021) The hierarchical packing of euchromatin domains can be described as multiplicative cascades, PLoS Computational Biology 17(5), p. e1008974, Public Library of Science, url, doi:10.1371/journal.pcbi.1008974

Agnieszka Pancholi, Tim Klingberg, Weichun Zhang, Roshan Prizak, Irina Mamontova, Amra Noa, A.Y. Kobitski, G.U. Nienhaus, Vasily Zaburdaev, Lennart Hilbert (2021) RNA polymerase II clusters form in line with liquid phase wetting of chromatin, bioRxiv, p. 2021.02.03.429626, Cold Spring Harbor Laboratory, url, doi:10.1101/2021.02.03.429626

Bart W. Hoogenboom, Loren E. Hough, Edward A. Lemke, Roderick Y.H. Lim, Patrick R. Onck, Anton Zilman (2021) Physics of the nuclear pore complex: Theory, modeling and experiment, Physics Reports 921, p. 1-53, North-Holland, doi:10.1016/j.physrep.2021.03.003

Amra Noa, Hui Shun Kuan, Vera Aschmann, Vasily Zaburdaev, Lennart Hilbert (2021) The hierarchical packing of euchromatin domains can be described as multiplicative cascades, PLoS Computational Biology 17(5), p. e1008974, Public Library of Science, url, doi:10.1371/journal.pcbi.1008974

Lara Aletta Gruijs da Silva, Francesca Simonetti, Saskia Hutten, Henrick Riemenschneider, Erin L Sternburg, Lisa M Pietrek, Jakob Gebel, Volker Doetsch, Dieter Edbauer, Gerhard Hummer, Lukas S Stelzl, Dorothee Dormann (2021) Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation, bioRxiv, p. 2021.04.30.442163, Cold Spring Harbor Laboratory, url, doi:10.1101/2021.04.30.442163

2020

A. Klosin, F. Oltsch, T. Harmon, A. Honigmann, F. JĂĽlicher, A. A. Hyman, C. Zechner (2020) Phase separation provides a mechanism to reduce noise in cells, Science 367(6476), p. 464-468, American Association for the Advancement of Science, url, doi:10.1126/SCIENCE.AAV6691/SUPPL_FILE/AAV6691S2.MOV

Anne Bremer, Tanja Mittag, Michael Heymann (2020) Microfluidic characterization of macromolecular liquid-liquid phase separation, Lab on a Chip 20(22), p. 4225-4234, The Royal Society of Chemistry, url, doi:10.1039/d0lc00613k

Sara Cuylen-Haering, Mina Petrovic, Alberto Hernandez-Armendariz, Maximilian W.G. Schneider, Matthias Samwer, Claudia Blaukopf, Liam J. Holt, Daniel W. Gerlich (2020) Chromosome clustering by Ki-67 excludes cytoplasm during nuclear assembly, Nature 2020 587:7833 587(7833), p. 285-290, Nature Publishing Group, url, doi:10.1038/s41586-020-2672-3

Johannes Söding, David Zwicker, Salma Sohrabi-Jahromi, Marc Boehning, Jan Kirschbaum (2020) Mechanisms for Active Regulation of Biomolecular Condensates, Trends in Cell Biology 30(1), p. 4-14, Elsevier, url, doi:10.1016/j.tcb.2019.10.006

Tina Ukmar-Godec, Susanne Wegmann, Markus Zweckstetter (2020) Biomolecular condensation of the microtubule-associated protein tau, Seminars in Cell & Developmental Biology 99, p. 202-214, Academic Press, doi:10.1016/J.SEMCDB.2019.06.007

Giorgia Celetti, Giulia Paci, Joana Caria, Virginia VanDelinder, George Bachand, Edward A. Lemke (2020) The liquid state of FG-nucleoporins mimics permeability barrier properties of nuclear pore complexes, Journal of Cell Biology 219(1), Rockefeller University Press, url, doi:10.1083/jcb.201907157

Jaroslaw Majewski, Emmalee M. Jones, Crystal M. Vander Zanden, Jacek Biernat, Eckhard Mandelkow, Eva Y. Chi (2020) Lipid membrane templated misfolding and self-assembly of intrinsically disordered tau protein, Scientific Reports 10(1), p. 1-13, Nature Publishing Group, url, doi:10.1038/s41598-020-70208-6

Ariel Erijman, Lukasz Kozlowski, Salma Sohrabi-Jahromi, James Fishburn, Linda Warfield, Jacob Schreiber, William S. Noble, Johannes Söding, Steven Hahn (2020) A High-Throughput Screen for Transcription Activation Domains Reveals Their Sequence Features and Permits Prediction by Deep Learning, Molecular Cell 78(5), p. 890-902.e6, Cell Press, doi:10.1016/j.molcel.2020.04.020

Nike HeinĂź, Mikhail Sushkin, Miao Yu, Edward A. Lemke (2020) Multifunctionality of F-rich nucleoporins, Biochemical Society Transactions 48(6), p. 2603-2614, Portland Press, url, doi:10.1042/BST20200357

Lukas Frank, Karsten Rippe (2020) Repetitive RNAs as Regulators of Chromatin-Associated Subcompartment Formation by Phase Separation, Journal of Molecular Biology 432(15), p. 4270-4286, Academic Press, doi:10.1016/j.jmb.2020.04.015

Carsten Donau, Fabian Späth, Marilyne Sosson, Brigitte A.K. Kriebisch, Fabian Schnitter, Marta Tena-Solsona, Hyun Seo Kang, Elia Salibi, Michael Sattler, Hannes Mutschler, Job Boekhoven (2020) Active coacervate droplets as a model for membraneless organelles and protocells, Nature Communications 11(1), p. 1-10, Nature Publishing Group, url, doi:10.1038/s41467-020-18815-9

Saskia Hutten, Dorothee Dormann (2020) A Quantitative Assay to Measure Stress Granule Association of Proteins and Peptides in Semi-permeabilized Human Cells, BIO-PROTOCOL 10(24), p. e3846, Bio Protoc, url, doi:10.21769/bioprotoc.3846

2019

Tina Ukmar-Godec, Saskia Hutten, Matthew P. Grieshop, Nasrollah Rezaei-Ghaleh, Maria Sol Cima-Omori, Jacek Biernat, Eckhard Mandelkow, Johannes Söding, Dorothee Dormann, Markus Zweckstetter (2019) Lysine/RNA-interactions drive and regulate biomolecular condensation, Nature Communications 10(1), p. 1-15, Nature Publishing Group, url, doi:10.1038/s41467-019-10792-y

Sara S. Ribeiro, Nirnay Samanta, Simon Ebbinghaus, JoĂŁo C. Marcos (2019) The synergic effect of water and biomolecules in intracellular phase separation, Nature Reviews Chemistry 3(9), p. 552-561, Nature Publishing Group, url, doi:10.1038/s41570-019-0120-4