2023
(2023) The endoplasmic reticulum puts a new spin on synaptic tagging, Trends in Neurosciences 46(1), p. 32-44, Elsevier Current Trends, doi:10.1016/J.TINS.2022.10.012
(2023) Light Microscopy and Dynamic Light Scattering to Study Liquid-Liquid Phase Separation of Tau Proteins In Vitro, Methods in Molecular Biology 2551, p. 225-243, Humana Press Inc., url, doi:10.1007/978-1-0716-2597-2_15/FIGURES/4
2022
(2022) High-speed fluorescence image-enabled cell sorting, Science 375(6578), p. 315-320, American Association for the Advancement of Science, url, doi:10.1126/SCIENCE.ABJ3013/SUPPL_FILE/SCIENCE.ABJ3013_MDAR_REPRODUCIBILITY_CHECKLIST.PDF
(2022) Correlative all-optical quantification of mass density and mechanics of subcellular compartments with fluorescence specificity, eLife 11, p. 68490, eLife Sciences Publications, Ltd, url, doi:10.7554/ELIFE.68490
(2022) Molecular crowding and RNA synergize to promote phase separation, microtubule interaction, and seeding of Tau condensates, The EMBO Journal, p. e108882, John Wiley & Sons, Ltd, url, doi:10.15252/EMBJ.2021108882
(2022) Sedimentation assays to assess the impact of post-translational modifications on phase separation of RNA-binding proteins in vitro and in cells, Methods Mol Biol, in press
(2022) Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation, EMBO J, in press
(2022) Post-translational modifications on RNA-binding proteins: accelerators, brakes, or passengers in neurodegeneration?, Trends in biochemical sciences 47(1), p. 6-22, Trends Biochem Sci, url, doi:10.1016/J.TIBS.2021.07.004
2021
(2021) Sequestration of Proteins in Stress Granules Relies on the In-Cell but Not the in Vitro Folding Stability, Journal of the American Chemical Society 143(47), p. 19909-19918, American Chemical Society, url, doi:10.1021/JACS.1C09589/SUPPL_FILE/JA1C09589_SI_001.PDF
(2021) Deep-learning microscopy image reconstruction with quality control reveals second-scale rearrangements in RNA polymerase II clusters, bioRxiv, p. 2021.12.05.471272, Cold Spring Harbor Laboratory, url, doi:10.1101/2021.12.05.471272
(2021) Controlling composition of coexisting phases via molecular transitions, Biophysical Journal 120(21), p. 4682-4697, Elsevier, url, doi:10.1016/j.bpj.2021.09.036
(2021) Thermodynamics of wetting, prewetting and surface phase transitions with surface binding, New Journal of Physics 23(12), p. 123003, IOP Publishing, url, doi:10.1088/1367-2630/ac320b
(2021) Quantitative theory for the diffusive dynamics of liquid condensates, eLife 10, eLife Sciences Publications Ltd, doi:10.7554/eLife.68620
(2021) Thermodynamic modeling reveals widespread multivalent binding by RNA-binding proteins, Bioinformatics 37(Supplement_1), p. I308-I316, Oxford Academic, url, doi:10.1093/bioinformatics/btab300
(2021) Tau and Membranes: Interactions That Promote Folding and Condensation, Frontiers in Cell and Developmental Biology 9, Front Cell Dev Biol, url, doi:10.3389/fcell.2021.725241
(2021) Disease-Associated Tau Phosphorylation Hinders Tubulin Assembly within Tau Condensates, Angewandte Chemie - International Edition 60(2), p. 726-730, John Wiley & Sons, Ltd, url, doi:10.1002/anie.202011157
(2021) A current view on Tau protein phosphorylation in Alzheimer's disease, Current Opinion in Neurobiology 69, p. 131-138, Curr Opin Neurobiol, url, doi:10.1016/j.conb.2021.03.003
(2021) Stress-induced nuclear condensation of NELF drives transcriptional downregulation, Molecular Cell 81(5), p. 1013-1026.e11, Mol Cell, url, doi:10.1016/j.molcel.2021.01.016
(2021) Role of Solvent Compatibility in the Phase Behavior of Binary Solutions of Weakly Associating Multivalent Polymers, Biomacromolecules 15, p. acs.biomac.1c01301, American Chemical Society, url, doi:10.1021/ACS.BIOMAC.1C01301
(2021) Reversible Kinetic Trapping of FUS Biomolecular Condensates, Advanced Science, p. 2104247, John Wiley & Sons, Ltd, url, doi:10.1002/ADVS.202104247
(2021) Transcriptional Activation of Heterochromatin by Recruitment of dCas9 Activators, Enhancer and Promotors. Methods in Molecular Biology 2351, T. Borggrefe, B.D. Giaimo (ed.), p. 307-320, Humana, New York, NY, url, doi:10.1007/978-1-0716-1597-3_17
(2021) Transcription activation is enhanced by multivalent interactions independent of liquid-liquid phase separation, bioRxiv, p. 2021.01.27.428421, Cold Spring Harbor Laboratory, url, doi:10.1101/2021.01.27.428421
(2021) The hierarchical packing of euchromatin domains can be described as multiplicative cascades, PLoS Computational Biology 17(5), p. e1008974, Public Library of Science, url, doi:10.1371/journal.pcbi.1008974
(2021) RNA polymerase II clusters form in line with liquid phase wetting of chromatin, bioRxiv, p. 2021.02.03.429626, Cold Spring Harbor Laboratory, url, doi:10.1101/2021.02.03.429626
(2021) Physics of the nuclear pore complex: Theory, modeling and experiment, Physics Reports 921, p. 1-53, North-Holland, doi:10.1016/j.physrep.2021.03.003
(2021) The hierarchical packing of euchromatin domains can be described as multiplicative cascades, PLoS Computational Biology 17(5), p. e1008974, Public Library of Science, url, doi:10.1371/journal.pcbi.1008974
(2021) Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation, bioRxiv, p. 2021.04.30.442163, Cold Spring Harbor Laboratory, url, doi:10.1101/2021.04.30.442163
2020
(2020) Phase separation provides a mechanism to reduce noise in cells, Science 367(6476), p. 464-468, American Association for the Advancement of Science, url, doi:10.1126/SCIENCE.AAV6691/SUPPL_FILE/AAV6691S2.MOV
(2020) Microfluidic characterization of macromolecular liquid-liquid phase separation, Lab on a Chip 20(22), p. 4225-4234, The Royal Society of Chemistry, url, doi:10.1039/d0lc00613k
(2020) Chromosome clustering by Ki-67 excludes cytoplasm during nuclear assembly, Nature 2020 587:7833 587(7833), p. 285-290, Nature Publishing Group, url, doi:10.1038/s41586-020-2672-3
(2020) Mechanisms for Active Regulation of Biomolecular Condensates, Trends in Cell Biology 30(1), p. 4-14, Elsevier, url, doi:10.1016/j.tcb.2019.10.006
(2020) Biomolecular condensation of the microtubule-associated protein tau, Seminars in Cell & Developmental Biology 99, p. 202-214, Academic Press, doi:10.1016/J.SEMCDB.2019.06.007
(2020) The liquid state of FG-nucleoporins mimics permeability barrier properties of nuclear pore complexes, Journal of Cell Biology 219(1), Rockefeller University Press, url, doi:10.1083/jcb.201907157
(2020) Lipid membrane templated misfolding and self-assembly of intrinsically disordered tau protein, Scientific Reports 10(1), p. 1-13, Nature Publishing Group, url, doi:10.1038/s41598-020-70208-6
(2020) A High-Throughput Screen for Transcription Activation Domains Reveals Their Sequence Features and Permits Prediction by Deep Learning, Molecular Cell 78(5), p. 890-902.e6, Cell Press, doi:10.1016/j.molcel.2020.04.020
(2020) Multifunctionality of F-rich nucleoporins, Biochemical Society Transactions 48(6), p. 2603-2614, Portland Press, url, doi:10.1042/BST20200357
(2020) Repetitive RNAs as Regulators of Chromatin-Associated Subcompartment Formation by Phase Separation, Journal of Molecular Biology 432(15), p. 4270-4286, Academic Press, doi:10.1016/j.jmb.2020.04.015
(2020) Active coacervate droplets as a model for membraneless organelles and protocells, Nature Communications 11(1), p. 1-10, Nature Publishing Group, url, doi:10.1038/s41467-020-18815-9
(2020) A Quantitative Assay to Measure Stress Granule Association of Proteins and Peptides in Semi-permeabilized Human Cells, BIO-PROTOCOL 10(24), p. e3846, Bio Protoc, url, doi:10.21769/bioprotoc.3846
2019
(2019) Lysine/RNA-interactions drive and regulate biomolecular condensation, Nature Communications 10(1), p. 1-15, Nature Publishing Group, url, doi:10.1038/s41467-019-10792-y
(2019) The synergic effect of water and biomolecules in intracellular phase separation, Nature Reviews Chemistry 3(9), p. 552-561, Nature Publishing Group, url, doi:10.1038/s41570-019-0120-4