GBM Compact and SPP2191 International Meeting

Dear friends and colleagues,

While the existence of membrane-less organelles, such as nucleoli, stress granules or Cajal bodies has been known for a long time, it has remained largely unclear how such organelles are actually formed, maintained and regulated. We now know that compartments can also be formed by the phase separation of proteins, RNA and DNA and combinations thereof.

To investigate the newly emerging role of phase separation in biology, we need to develop new tools and approaches, as well as combine cell biology and biophysics with biochemical reconstitution, theory and modelling.

This meeting will bring together scientists from different disciplines which will synergistically decipher how novel functions and pathologies emerge from the process of phase separation in biological systems, and what molecular underpinnings facilitate and regulate this key process.

We are looking forward to an exciting meeting and cordially invite you to participate!

The meeting of the priority program 2191 on the Molecular Mechanism of Functional Phase separation will precede the GBM compact with the aim to extend this 1.5-day meeting by another 1.5-day meeting. It will bring additional talks and poster sessions from members of the priority program as well as a keynote talk on “Complex intrinsic and RNA-dependent phase behaviors of RRM-containing proteins” by Rohit Pappu from Washington University in St. Louis. We would be excited to additionally welcome you to this event.

Simon Alberti / Sara Cuylen-Haering / Dorothee Dormann / Edward Lemke / Julia Mahamid / Claus Seidel / Konstanze Winklhofer